Why women drunk easier

Doctors are men who prescribe medicines of which they know little, to cure diseases of which they know less, in human beings of whom they know nothing. Voltaire, witty French asshole

GM 🦁 This is Andrew's Apples, the health email that's like a good gluten-free pizza - fairly healthy but still kills when drunk. Gimme 2 min of your time. Let's go.

1. 💊 Diet pills that work? A new drug for treatment of obesity was just approved, and evidently with few if any side effects (so far). Taken once weekly, the group with the highest dosage lost as much as 21% (i.e. 50-60 pounds) of their body weight. Diet pills have been in the American public consciousness since the 1950s, but always with many consequences and only cut up to 5% of weight. This could be HUGE for people struggling with serious obesity (and recall that if aging is the mother of all disease, obesity is the father). "The drug, called tirzepatide, works on two naturally occurring hormones that help control blood sugar and are involved in sending fullness signals from the gut to the brain." We will continue to monitor the implementation of these drugs and their side effects, but it's an askterisk'd win for the time being.

2. 🍷 Why women drunk easier. I know, that was a drunk sentence. I have always assumed that the reason that women get drunk more easily than men is because they are smaller in size. And I would be partly correct in that assumption. There is more to the story, though. The NIAAA defines heavy drinking for men as >14 drinks per week and for women a mere >7 drinks per week. Twice as much for men, sheesh! Aside from being smaller in size, women have higher percent body fat (less water to dilute the alcohol) and reduced metabolism enzymes to break down said alcohol. Like all biology, it's not fair, it just is. Ladies: despite what your S.O. says about himself, he's not "a tank." And certainly nor are you. Proust!

3. 🏋️ The sit-up is dead. I'm a 90s baby so I still vividly recall the arm hang, jumping jack, jump rope, sit-and-reach, chin up, and the partner-holds-your-feet down SIT-UP! Well, according to The Atlantic, it's over. I feel two ways about this news: (1) sad and nostalgic for something that got kids to channel their manic energy into something productive that ultimately, after 30 or 40, hurt... pain is weakness leaving the body and all that (2) the sit-up when performed in rapid succession led to lower-back injuries and tricked practitioners into thinking that isolating one body part was a smart way to improve said body part (e.g. doing sit-ups to lose belly fat). We have countless compound exercises that work the core in a more conducive way, hitting more muscle groups at once. But still, a tear rides down my cheek thinking about racing my friends in gym class until I cracked a rib.

4. 🕊️ Tweet of the Day. By and large the quality of one's skin reflects the quality of what's underneath. I would modify his to-do list to: sunlight, exercise, no soaps on the face, lots of electrolyte water (no need to freak out re source of water), minimize sugar, anything that lowers stress (music, walks, friends, reading), and good sex with non-strangers. Products from The Ordinary are clinician-approved and scary cheap. Godspeed... and tbh a little acne is kinda cute.

How do you like them Apples? If you ever need anything, hit reply. Love hearing from readers.

Your friend,

Andrew🍎

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